The mother of thousands prefers a bright spot in your home where it can appreciate several hours of direct light if possible.
As with most succulents, your Kalanchoe daigremontiana will need a well-drained potting medium—standing water is a big issue for this plant. Many enthusiasts use a cactus mix, and others might mix sand or perliteinto a standard potting soil. Using a clay potis desirable; it helps absorb excess moisture and takes it away from the plant.
The mother of thousands is drought tolerant, but not as much as many succulent species. It'll do better if it receives regular and gradual hydration, especially during its growing season. Still, it only needs water once every few weeks, even in spring and summer. It won't be a major problem if you forget now and again.
Once the first couple of inches of the soil surface is dry, then you should rewater. By gradually dampening the soil, you won't risk over-saturating the roots. During the fall and winter, reduce watering. Overwatering will cause limp leaves.